The EPA's CERCLIS Database is the Comprehensive Environmental Response, Compensation and Liability Information System that contains information on hazardous waste sites, potentially hazardous waste sites and remedial activities across the nation.

The CERCLIS Database, to be retired, will be folded into the SEMS Database. The Superfund Enterprise Management System is a computer application that EPA has built over the past several years. Once active, the new SEMS system will integrate under one umbrella the functions that formerly resided in the old CERCLIS application, the SDMS (Superfund Document Management System) and a few other internally facing EPA applications. SEMS will house the traditional CERCLIS data that environmental consultants are accustomed to seeing in their EDR Reports.